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Daphne Blake is a rich and fashionable member of Mystery Inc.. This page is for additional biographical facts about her that can be gathered from the video games.
- Uncle Blake: Daphne's uncle and also a hotel owner of Blake's Hotel. (Scooby-Doo Mystery (Sega Genesis))
- Aunt Mabel: Daphne's aunt, who works at Bradshaw Manor. (Scooby-Doo Mystery (Snes))
- Anna Blake: a cousin who attended St. Louis High School (Scooby-Doo! First Frights)