|This needs a stretch.|
Needed: Physical appearance.
She gained a large exaggerated wolf-face in place of her own.
The 13 Ghosts of Scooby-Doo
While stranded in the Himalayas, Daphne was tricked into drinking a potion that turned everyone into werewolves. After her transformation was complete, she and the townspeople chased Shaggy and Scooby, who hid in the sewer. When Flim-Flam splashed some of his Lotsa Luck Joy Juice on her, Daphne turned back to normal.