Mr. Blake may refer to a father or another relative from different incarnations of Daphne Blake:
- Nedley Blake: The father of Daphne in standard continuity, who appeared in The New Scooby and Scrappy Doo Show and A Pup Named Scooby-Doo.
- Mr. Blake: Daphne mentioned her both her parents in the Scooby-Doo! The Mystery Begins continuity.
- Barty Blake: The father of Daphne in the Scooby-Doo! Mystery Incorporated continuity.
- Ned Blake: The father of Daphne in the Scooby Apocalypse continuity.