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- Dr. Phineus Phibes (main story and flashback)
- Agent 1
- Agent 2/
- Big Red (single appearance)(disguise)
- Agent 4 (no lines)
- Dr. Trebla
- Super bulls (single appearance)(no lines)
- Cocky (single appearance)(no lines)
- Man from Phibes's childhood 1 (single appearance)(flashback only)
- Man from Phibes's childhood 2 (single appearance)(no lines)(flashback only)
- Pig (single appearance)(no lines)
- Decider (single appearance)
|Scott Menville|| Shaggy Rogers|
|Jeff Bennett|| Dr. Phineus Phibes|
|Jim Meskimen|| Robi|
|Casey Kasem||Dr. Albert Shaggleford|
- Shaggy sets out on the mission dressed in a similar style to Clint Eastwood in A Fistful of Dollars.
- It is possible that the Tri-State Fair is a Phineas and Ferb homage, since that show was previewed on the Disney Channel about a year before this episode came out. The mad scientist on that show is always trying to take over the "Tri-State Area," and trying to avenge childhood insults.
- Characters who are parodies of George Bush and Dick Cheney make a cameo appearance at a barbeque contest.
In other languages
|Spanish (Latin America)||Los Vaqueros Detectives||The Cowboy Detectives|
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|Don't Get a Big Head|| Shaggy & Scooby-Doo Get a Clue!|
|Zoinks the Wonder Dog|